AMG-416

Modify Date: 2024-01-08 19:17:46

AMG-416 structure	Common Name	AMG-416
	CAS Number	1334237-71-6	Molecular Weight	1084.712
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₇₃N₂₁O₁₀S_2.xClH	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AMG-416

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

Name	etelcalcetide hydrochloride
Synonym	More Synonyms

Description	Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> CaSR
References	[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.

Molecular Formula	C₃₈H₇₃N₂₁O₁₀S_2.xClH
Molecular Weight	1084.712
Exact Mass	1083.505737

(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)

AMG 416

velcalcetide hydrochloride

etelcalcetide hydrochloride

KAI-4169

UNII:72PT5993DU

AMG-416