Hydroxy-PEG2-acid

Modify Date: 2024-01-03 10:10:46

Hydroxy-PEG2-acid Structure
Hydroxy-PEG2-acid structure
Common Name Hydroxy-PEG2-acid
CAS Number 1334286-77-9 Molecular Weight 178.18306
Density N/A Boiling Point N/A
Molecular Formula C7H14O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG2-acid


Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
Synonym More Synonyms

 Hydroxy-PEG2-acid Biological Activity

Description Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C7H14O5
Molecular Weight 178.18306

 Synonyms

MFCD20646030
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