DS-1040

Modify Date: 2024-08-13 12:05:20

DS-1040 Structure
DS-1040 structure
Common Name DS-1040
CAS Number 1335138-62-9 Molecular Weight 293.411
Density N/A Boiling Point N/A
Molecular Formula C16H27N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DS-1040


DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical

 Names

Name DS-1040

 DS-1040 Biological Activity

Description DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical
References References 1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971. 2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081. 3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282. View Related Products by Target Other Targets Stroke

 Chemical & Physical Properties

Molecular Formula C16H27N3O2
Molecular Weight 293.411
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