DS-1040 tosylate hydrate
Modify Date: 2024-01-18 21:54:52
DS-1040 tosylate hydrate structure
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Common Name | DS-1040 tosylate hydrate | ||
|---|---|---|---|---|
| CAS Number | 1335138-90-3 | Molecular Weight | 483.624 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H37N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DS-1040 tosylate hydrateDS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical |
| Name | DS-1040 tosylate hydrate |
|---|
| Description | DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical |
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| References | References 1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971. 2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081. 3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282. View Related Products by Target Other Targets Stroke |
| Molecular Formula | C23H37N3O6S |
|---|---|
| Molecular Weight | 483.624 |