Misoprostol acid D5

Modify Date: 2024-01-02 18:36:31

Misoprostol acid D5 Structure
Misoprostol acid D5 structure
Common Name Misoprostol acid D5
CAS Number 1337917-44-8 Molecular Weight 373.538
Density 1.1±0.1 g/cm3 Boiling Point 538.3±50.0 °C at 760 mmHg
Molecular Formula C21H31D5O5 Melting Point N/A
MSDS N/A Flash Point 293.4±26.6 °C

 Use of Misoprostol acid D5


Misoprostol acid D5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].

 Names

Name (11α,13E)-11,16-Dihydroxy-16-(2H3)methyl-9-oxo(17,17-2H2)prost-13-en-1-oic acid
Synonym More Synonyms

 Misoprostol acid D5 Biological Activity

Description Misoprostol acid D5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
Related Catalog
References

[1]. Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879(26):2827-33.

[2]. Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 538.3±50.0 °C at 760 mmHg
Molecular Formula C21H31D5O5
Molecular Weight 373.538
Flash Point 293.4±26.6 °C
Exact Mass 373.287659
PSA 94.83000
LogP 2.45
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.543

 Synonyms

Prost-13-en-1-oic-17,17-d acid, 11,16-dihydroxy-16-(methyl-d)-9-oxo-, (11α,13E)-
(11α,13E)-11,16-Dihydroxy-16-(H)methyl-9-oxo(17,17-H)prost-13-en-1-oic acid