1337917-44-8

1337917-44-8 structure

Name: Misoprostol acid D5
Chemical Name: (11α,13E)-11,16-Dihydroxy-16-(2H3)methyl-9-oxo(17,17-2H2)prost-13-en-1-oic acid
CAS Number: 1337917-44-8
Molecular Formula: C₂₁H₃₁D₅O₅
Molecular Weight: 373.538
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2017-06-13 08:53:57
Modify Date: 2024-01-02 18:36:31
Misoprostol acid D5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].

Name	(11α,13E)-11,16-Dihydroxy-16-(2H3)methyl-9-oxo(17,17-2H2)prost-13-en-1-oic acid
Synonyms	Prost-13-en-1-oic-17,17-d acid, 11,16-dihydroxy-16-(methyl-d)-9-oxo-, (11α,13E)- (11α,13E)-11,16-Dihydroxy-16-(H)methyl-9-oxo(17,17-H)prost-13-en-1-oic acid

Description	Misoprostol acid D5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
References	[1]. Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879(26):2827-33. [2]. Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448.