Rimantadine
Modify Date: 2024-01-02 08:13:41
Rimantadine structure
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Common Name | Rimantadine | ||
|---|---|---|---|---|
| CAS Number | 13392-28-4 | Molecular Weight | 179.30 | |
| Density | 1.033 | Boiling Point | 248ºC | |
| Molecular Formula | C12H21N | Melting Point | 375°C(lit.) | |
| MSDS | N/A | Flash Point | 99ºC | |
Use of RimantadineRimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. |
| Name | 1-(1-adamantyl)ethanamine |
|---|---|
| Synonym | More Synonyms |
| Description | Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. |
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| Related Catalog | |
| References |
| Density | 1.033 |
|---|---|
| Boiling Point | 248ºC |
| Melting Point | 375°C(lit.) |
| Molecular Formula | C12H21N |
| Molecular Weight | 179.30 |
| Flash Point | 99ºC |
| PSA | 26.02000 |
| LogP | 4.05230 |
| Vapour Pressure | 0.0249mmHg at 25°C |
| Index of Refraction | 1.539 |
| Storage condition | -20°C |
CHEMICAL IDENTIFICATION
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| Hazard Codes | Xn |
|---|---|
| HS Code | 2921300090 |
|
~98%
Rimantadine CAS#:13392-28-4 |
| Literature: E. I. Du Pont de Nemours and Company Patent: US4551552 A1, 1985 ; |
|
~85%
Rimantadine CAS#:13392-28-4 |
| Literature: Vashkevich; Kozlov; Potkin Russian Journal of Organic Chemistry, 1999 , vol. 35, # 12 p. 1773 - 1776 |
|
~%
Rimantadine CAS#:13392-28-4 |
| Literature: Journal of medicinal chemistry, , vol. 14, # 6 p. 535 - 543 |
CAS#:90812-24-1| HS Code | 2921300090 |
|---|---|
| Summary | 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
| 1-adamantanemethylamine |
| tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride |
| a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride |
| Remantadine |
| Meradan |
| α-Methyl-1-adamantanemethylamine hydrochloride |
| UNII:JEI07OOS8Y |
| [1-(1-Adamantyl)ethyl]amine hydrochloride |
| Rimant |
| MFCD03265511 |
| 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate |
| 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1) |
| Roflual |
| Rimantadinum |
| 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1) |
| Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1) |
| Flumadine |
| a-Methyl-1-adamantanemethylamine Hydrochloride |
| 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid |
| Rimantadina |
| Rimantadine |
| Rimantadine Hydrochloride |
| 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride |
| Riamantadine |
| Remantadine hydrochloride |