N-Boc-PEG8-alcohol

Modify Date: 2024-01-09 18:50:26

N-Boc-PEG8-alcohol Structure
N-Boc-PEG8-alcohol structure
Common Name N-Boc-PEG8-alcohol
CAS Number 1345337-22-5 Molecular Weight 297.30376
Density N/A Boiling Point N/A
Molecular Formula C21H43NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-PEG8-alcohol


N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Z-8-aMino-3,6-dioxaoctanoic acid
Synonym More Synonyms

 N-Boc-PEG8-alcohol Biological Activity

Description N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H43NO10
Molecular Weight 297.30376

 Synonyms

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID