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106984-09-2

106984-09-2 structure
106984-09-2 structure
  • Name: N-Boc-PEG4-alcohol
  • Chemical Name: 1-Boc-amino-3,6,9-trioxaundecanyl-11-ol
  • CAS Number: 106984-09-2
  • Molecular Formula: C13H27NO6
  • Molecular Weight: 293.35700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-07-18 21:48:42
  • Modify Date: 2024-01-06 14:42:34
  • PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name 1-Boc-amino-3,6,9-trioxaundecanyl-11-ol
Synonyms tert-butyl N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]carbamate
N-Boc-PEG4-alcohol
Description PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.078g/cm3
Boiling Point 414ºC at 760mmHg
Molecular Formula C13H27NO6
Molecular Weight 293.35700
Flash Point 204.2ºC
Exact Mass 293.18400
PSA 86.25000
LogP 0.94410
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.459
Hazard Codes Xn
HS Code 2924199090
HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%