ML-241

Modify Date: 2024-01-29 18:26:24

ML-241 Structure
ML-241 structure
Common Name ML-241
CAS Number 1346528-06-0 Molecular Weight 372.46
Density 1.3±0.1 g/cm3 Boiling Point 600.3±65.0 °C at 760 mmHg
Molecular Formula C23H24N4O Melting Point N/A
MSDS N/A Flash Point 316.9±34.3 °C

 Use of ML-241


ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC50 of 0.11 μM. ML241 can be used for the research of cancer[1].

 Names

Name N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine
Synonym More Synonyms

 ML-241 Biological Activity

Description ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC50 of 0.11 μM. ML241 can be used for the research of cancer[1].
Related Catalog
Target

IC50: 0.11 μM (p97 ATPase)[1] Ki: 0.35 μM (p97 ATPase)[1]

References

[1]. Chou TF, et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem. 2013 Feb;8(2):297-312.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 600.3±65.0 °C at 760 mmHg
Molecular Formula C23H24N4O
Molecular Weight 372.46
Flash Point 316.9±34.3 °C
Exact Mass 372.195007
LogP 3.45
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.669
Storage condition -20℃

 Synonyms

N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine
4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-
ML-241
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