9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine

Modify Date: 2024-08-09 18:22:54

9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine Structure
9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine structure
Common Name 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine
CAS Number 1347118-41-5 Molecular Weight 416.82
Density 1.5±0.1 g/cm3 Boiling Point 592.2±60.0 °C at 760 mmHg
Molecular Formula C19H17ClN4O5 Melting Point N/A
MSDS N/A Flash Point 312.0±32.9 °C

 Use of 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine


9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-(2-O-Acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-6-chloro-9H-purine
Synonym More Synonyms

  Biological Activity

Description 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 592.2±60.0 °C at 760 mmHg
Molecular Formula C19H17ClN4O5
Molecular Weight 416.82
Flash Point 312.0±32.9 °C
Exact Mass 416.088745
LogP 2.60
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.686

 Synonyms

9-(2-O-Acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-6-chloro-9H-purine
9H-Purine, 9-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-6-chloro-