Bullatine A

Modify Date: 2024-01-03 15:29:03

Bullatine A structure	Common Name	Bullatine A
	CAS Number	1354-84-3	Molecular Weight	343.503
	Density	1.2±0.1 g/cm3	Boiling Point	488.2±45.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₃NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	242.3±27.4 °C

Use of Bullatine A

Bullatine A (BLA), a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A (BLA) is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses[1].Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed[2].

Name	Bullatine A
Synonym	More Synonyms

Description	Bullatine A (BLA), a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A (BLA) is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses[1].Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed[2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor
References	[1]. Li J, et al. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways. Brain Res Bull. 2013 Aug;97:81-5. [2]. Huang Q, et al. Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. J Neuroinflammation. 2016 Aug 30;13(1):214.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor

References

[1]. Li J, et al. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways. Brain Res Bull. 2013 Aug;97:81-5.

[2]. Huang Q, et al. Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. J Neuroinflammation. 2016 Aug 30;13(1):214.

Density	1.2±0.1 g/cm3
Boiling Point	488.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₃NO₂
Molecular Weight	343.503
Flash Point	242.3±27.4 °C
Exact Mass	343.251129
PSA	43.70000
LogP	3.07
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.620

HS Code	29339900

21-Ethyl-4-methyl-7,20-cycloatid-16-ene-11,15-diol

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bullatine A
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Bullatine A
Price: ￥588.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Bullatine A
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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