DMT1 blocker 1

Modify Date: 2024-01-13 20:44:59

DMT1 blocker 1 Structure
DMT1 blocker 1 structure
Common Name DMT1 blocker 1
CAS Number 1354790-56-9 Molecular Weight 294.31
Density N/A Boiling Point N/A
Molecular Formula C16H14N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DMT1 blocker 1


DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1].

 Names

Name DMT1 blocker 1

 DMT1 blocker 1 Biological Activity

Description DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1].
Related Catalog
Target

IC50: 0.64 μM (DMT1 blocker 1)[1]

References

[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.

 Chemical & Physical Properties

Molecular Formula C16H14N4O2
Molecular Weight 294.31