PKC substrate (MBP)

Modify Date: 2024-01-08 19:06:00

PKC substrate (MBP) Structure
PKC substrate (MBP) structure
 Common Name PKC substrate (MBP)
CAS Number 136132-68-8 Molecular Weight 1373.56000
Density N/A Boiling Point N/A
Molecular Formula C60H100N20O17 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of PKC substrate (MBP)


[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].

 Names

Name [pGlu4]-Myelin basic protein fragment 4-14
Synonym More Synonyms

 PKC substrate (MBP) Biological Activity

Description [pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].
Related Catalog
References

[1]. Durocher Y, et al. Activation of an 85 kDa ribosomal S6 kinase during serotonin-induced oocyte maturation. Int J Dev Biol. 1996 Jun;40(3):557-66.  

[2]. Loog M, et al. Comparison of Substrate Specificities of Protein Kinases A and C Based on Peptide Substrates[J]. Bioorganic Chemistry, 1994, 22(3): 328-336.

 Chemical & Physical Properties

Molecular Formula C60H100N20O17
Molecular Weight 1373.56000
Exact Mass 1372.76000
PSA 628.23000
LogP 1.00040

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles1

More Articles
A synthetic peptide substrate for selective assay of protein kinase C.

Biochem. Biophys. Res. Commun. 166 , 1220, (1990)

Among various phosphate acceptor proteins and peptides so far tested, a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, Gln-Lys-Arg-Pro-Ser(8)-Gln-Arg-Ser-Lys-Tyr-Leu...

 Synonyms

pGlu-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu
MBP 4-14
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