Dermaseptin

Modify Date: 2024-01-11 16:57:43

Dermaseptin structure	Common Name	Dermaseptin
	CAS Number	136212-91-4	Molecular Weight	3455.06
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅₂H₂₅₇N₄₃O₄₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dermaseptin

Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi and protozoa.

Name	Dermaseptin from Phyllomedusa sauvagii
Synonym	More Synonyms

Description	Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi and protozoa.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection Natural Products >> Others Peptides
In Vitro	Dermaseptin is a water-soluble, thermostable, and nonhemolytic peptide endowed with highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. Circular dichroism spectra of dermaseptin in hydrophobic media indicated 80% alpha-helical conformation, and predictions of secondary structure suggested that dermaseptin can be configured as an amphiphatic alpha-helix spanning over residues 1-27, a structure that perturbs membrane functions regulating water flux[1]. Dermaseptin exerts a lytic action upon bacteria, protozoa, yeasts, and filamentous fungi at micromolar concentrations. Molecular elements responsible for the exceptional antimicrobial potency of dermaseptin are to be traced to the NH2-terminal alpha-helical amphipathic segment spanning residues 1-18 of the molecule[1].
References	[1]. Mor A, et al. Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin. Biochemistry. 1991 Sep 10;30(36):8824-30. [2]. Mor A, et al. The NH2-terminal alpha-helical domain 1-18 of dermaseptin is responsible for antimicrobial activity. J Biol Chem. 1994 Jan 21;269(3):1934-9.

Molecular Formula	C₁₅₂H₂₅₇N₄₃O₄₄S₂
Molecular Weight	3455.06
Storage condition	-20°C

Hazard Codes	Xi
Safety Phrases	22-24/25
WGK Germany	3.0

Dermaseptin

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DermaseptinfromPhyllomedusasauvagii
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DERMASEPTIN PHYLLOMEDUSA SAUVAGII
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: Dermaseptin
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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Price: $228/500ug

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