3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine

Modify Date: 2024-03-07 16:30:44

3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine Structure
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine structure
Common Name 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine
CAS Number 136675-87-1 Molecular Weight 438.41
Density 1.4±0.1 g/cm3 Boiling Point 585.4±60.0 °C at 760 mmHg
Molecular Formula C23H19FN2O6 Melting Point N/A
MSDS N/A Flash Point 307.8±32.9 °C

 Use of 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine


3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone
Synonym More Synonyms

  Biological Activity

Description 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 585.4±60.0 °C at 760 mmHg
Molecular Formula C23H19FN2O6
Molecular Weight 438.41
Flash Point 307.8±32.9 °C
Exact Mass 438.122711
LogP 3.77
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.621

 Synonyms

2(1H)-Pyrimidinone, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone