1-Dehydro-[10]-gingerdione

Modify Date: 2024-01-04 13:21:37

1-Dehydro-[10]-gingerdione Structure
1-Dehydro-[10]-gingerdione structure
 Common Name 1-Dehydro-[10]-gingerdione
CAS Number 136826-50-1 Molecular Weight 346.461
Density 1.1±0.1 g/cm3 Boiling Point 495.2±40.0 °C at 760 mmHg
Molecular Formula C21H30O4 Melting Point N/A
MSDS N/A Flash Point 166.3±20.8 °C

 Use of 1-Dehydro-[10]-gingerdione


1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS-induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research[1].

 Names

Name 1-Dehydro-10-gingerdione
Synonym More Synonyms

 1-Dehydro-[10]-gingerdione Biological Activity

Description 1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS-induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research[1].
Related Catalog
References

[1]. Hwa Young Lee, et al. 1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes. Br J Pharmacol. 2012 Sep;167(1):128-40.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 495.2±40.0 °C at 760 mmHg
Molecular Formula C21H30O4
Molecular Weight 346.461
Flash Point 166.3±20.8 °C
Exact Mass 346.214417
LogP 5.51
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.531

 Synonyms

1-Tetradecene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-, (1E)-
(1E)-1-(4-Hydroxy-3-methoxyphenyl)-1-tetradecene-3,5-dione
Top Suppliers:I want be here

Get all suppliers and price by the below link:

1-Dehydro-[10]-gingerdione suppliers

1-Dehydro-[10]-gingerdione price

Related Compounds: More...
1-Dehydro-6-gingerdione
76060-35-0
1-[10-[4-(dimethylamino)pyridin-1-ium-1-yl]decyl]-N,N-dimethylpyridin-1-ium-4-amine,dibromide
99082-26-5
1,10-dimethoxy-9-methyl-3-pentyl-6H-benzo[c]chromen-6-one
86253-88-5
1-(10-phenyl-3,4-dihydro-1H-benzo[b][1,6]naphthyridin-2-yl)ethanone
61712-44-5
1,10-phenanthroline-4-carbonitrile
31301-32-3
1,10-diethoxydeca-1,9-diyne
646057-34-3
1,10-Phenanthroline-5,6-dione
27318-90-7
1-(10-phenyldecyl)-1,2,4-triazole
919800-86-5
1,10-bis(4,4-dimethylpiperazin-4-ium-1-yl)decane-1,10-dione
61167-37-1
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
3-Amino-4-methyl-4-phenylpentanoic acid
2229464-35-9
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
849349-65-1
Chemsrc provides 1-Dehydro-[10]-gingerdione(CAS#:136826-50-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 1-Dehydro-[10]-gingerdione are included as well.>> amp version: 1-Dehydro-[10]-gingerdione

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved