Olivetol-d9

Modify Date: 2024-01-14 09:42:55

Olivetol-d9 Structure
Olivetol-d9 structure
Common Name Olivetol-d9
CAS Number 137125-92-9 Molecular Weight 189.29900
Density N/A Boiling Point N/A
Molecular Formula C11H7D9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Olivetol-d9


Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activi

 Names

Name 5-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)benzene-1,3-diol
Synonym More Synonyms

 Olivetol-d9 Biological Activity

Description Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activi
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Jiang R, et al. Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19. Drug Metab Pharmacokinet. 2013;28(4):332-8.;Yamaori S, et al. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab

 Chemical & Physical Properties

Molecular Formula C11H7D9O2
Molecular Weight 189.29900
Exact Mass 189.17200
PSA 40.46000
LogP 2.83050

 Synonyms

1,3-Dihydroxy-5-pentylbenzene-d9
3,5-Dihydroxyamylbenzene-d9
5-Pentyl-1,3-benzenediol-d9
Olivetol-d9
5-n-Amylresorcinol-d9
5-n-Pentylresorcinol-d9