137125-92-9

137125-92-9 structure

Name: Olivetol-d9
Chemical Name: 5-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)benzene-1,3-diol
CAS Number: 137125-92-9
Molecular Formula: C₁₁H₇D₉O₂
Molecular Weight: 189.29900
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2017-04-20 19:43:29
Modify Date: 2024-01-14 09:42:55
Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activi

Name	5-(2,2,3,3,4,4,5,5,5-nonadeuteriopentyl)benzene-1,3-diol
Synonyms	1,3-Dihydroxy-5-pentylbenzene-d9 3,5-Dihydroxyamylbenzene-d9 5-Pentyl-1,3-benzenediol-d9 Olivetol-d9 5-n-Amylresorcinol-d9 5-n-Pentylresorcinol-d9

Description	Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activi
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Jiang R, et al. Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19. Drug Metab Pharmacokinet. 2013;28(4):332-8.;Yamaori S, et al. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab