DYRKs-IN-2

Modify Date: 2024-01-10 10:30:02

DYRKs-IN-2 Structure
DYRKs-IN-2 structure
Common Name DYRKs-IN-2
CAS Number 1386980-04-6 Molecular Weight 632.16
Density N/A Boiling Point N/A
Molecular Formula C32H38ClN9O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DYRKs-IN-2


DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].

 Names

Name DYRKs-IN-2

 DYRKs-IN-2 Biological Activity

Description DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].
Related Catalog
Target

IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2]

In Vitro DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1].
References

[1]. Kevin Anderson, et al. Pyrido pyrimidines. US20120184542A1

 Chemical & Physical Properties

Molecular Formula C32H38ClN9O3
Molecular Weight 632.16