(2S)-Octyl-α-hydroxyglutarate

Modify Date: 2024-01-10 17:17:34

(2S)-Octyl-α-hydroxyglutarate structure	Common Name	(2S)-Octyl-α-hydroxyglutarate
	CAS Number	1391194-64-1	Molecular Weight	260.327
	Density	1.1±0.1 g/cm3	Boiling Point	420.5±35.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₂₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	152.3±19.4 °C

Use of (2S)-Octyl-α-hydroxyglutarate

(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

Name	(2S)-Octyl-α-hydroxyglutarate
Synonym	More Synonyms

Description	(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
In Vitro	Treatment of IDH1-WT HeLa cells with (2S)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells[1].
References	[1]. Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).

Pentanedioic acid, 2-hydroxy-, 1-octyl ester, (2S)-

(4S)-4-Hydroxy-5-(octyloxy)-5-oxopentanoic acid

MFCD29045545

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