Thiol-PEG2-t-butyl ester

Modify Date: 2024-01-10 18:07:34

Thiol-PEG2-t-butyl ester Structure
Thiol-PEG2-t-butyl ester structure
Common Name Thiol-PEG2-t-butyl ester
CAS Number 1398044-50-2 Molecular Weight 250.355
Density 1.0±0.1 g/cm3 Boiling Point 330.6±27.0 °C at 760 mmHg
Molecular Formula C11H22O4S Melting Point N/A
MSDS N/A Flash Point 200.0±11.6 °C

 Use of Thiol-PEG2-t-butyl ester


Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thio-PEG2-t-butyl ester
Synonym More Synonyms

 Thiol-PEG2-t-butyl ester Biological Activity

Description Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 330.6±27.0 °C at 760 mmHg
Molecular Formula C11H22O4S
Molecular Weight 250.355
Flash Point 200.0±11.6 °C
Exact Mass 250.123886
LogP 1.75
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.462

 Synonyms

Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-, 1,1-dimethylethyl ester
MFCD22574781
2-Methyl-2-propanyl 3-[2-(2-sulfanylethoxy)ethoxy]propanoate
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Thiol-PEG2-t-butyl ester suppliers

Thiol-PEG2-t-butyl ester price