JAK-IN-3

Modify Date: 2024-01-10 14:04:01

JAK-IN-3 structure	Common Name	JAK-IN-3
	CAS Number	1400876-94-9	Molecular Weight	340.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₀N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK-IN-3

JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].

Name	JAK-IN-3

Description	JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Others
Target	JAK3:3 nM (IC50) JAK1:5 nM (IC50) Tyk2:34 nM (IC50) JAK2:70 nM (IC50)
References	[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

Molecular Formula	C₁₈H₂₀N₄O₃
Molecular Weight	340.38