Cdc7-IN-1

Modify Date: 2024-01-16 10:07:17

Cdc7-IN-1 structure	Common Name	Cdc7-IN-1
	CAS Number	1402055-25-7	Molecular Weight	409.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₆ClN₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cdc7-IN-1

Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].

Name	Cdc7-IN-1

Description	Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	IC50: 0.6 nM (Cdc7, at 1 mM ATP)[1]
References	[1]. Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.

Molecular Formula	C₂₁H₁₆ClN₃O₄
Molecular Weight	409.82

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cdc7-IN-1
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Purity: 98.0%
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