eIF4A3-IN-9

Modify Date: 2024-04-07 11:10:07

eIF4A3-IN-9 Structure
eIF4A3-IN-9 structure
Common Name eIF4A3-IN-9
CAS Number 1402931-71-8 Molecular Weight 505.52
Density N/A Boiling Point N/A
Molecular Formula C28H27NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of eIF4A3-IN-9


eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis[1].

 Names

Name eIF4A3-IN-9

 eIF4A3-IN-9 Biological Activity

Description eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis[1].
Related Catalog
References

[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.  

 Chemical & Physical Properties

Molecular Formula C28H27NO8
Molecular Weight 505.52