2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

Modify Date: 2024-01-04 12:18:18

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite Structure
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite structure
Common Name 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
CAS Number 1404463-12-2 Molecular Weight 851.9
Density N/A Boiling Point N/A
Molecular Formula C46H51FN5O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite


2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 2'-Fluoro-2'-deoxy-ara-C-3'-phosphoramidite

  Biological Activity

Description 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Molecular Formula C46H51FN5O8P
Molecular Weight 851.9
Storage condition 2-8℃