2'-F-2'-ara-N2-ibu-dG Phosphoramidite

Modify Date: 2024-01-11 20:33:00

2'-F-2'-ara-N2-ibu-dG Phosphoramidite structure	Common Name	2'-F-2'-ara-N2-ibu-dG Phosphoramidite
	CAS Number	1404463-20-2	Molecular Weight	856.92
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₅H₅₄FN₆O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-F-2'-ara-N2-ibu-dG Phosphoramidite

2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	2'-F-2'-ara-ibu-dG Phosphoramidite

Description	2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₄₅H₅₄FN₆O₈P
Molecular Weight	856.92
Exact Mass	857.367737
LogP	9.87
Storage condition	2-8℃

2'-F-2'-ara-N2-ibu-dG Phosphoramidite

Use of 2'-F-2'-ara-N2-ibu-dG Phosphoramidite

Names

2'-F-2'-ara-N2-ibu-dG Phosphoramidite Biological Activity

Chemical & Physical Properties