2-Keto Crizotinib
Modify Date: 2024-01-11 13:53:16
2-Keto Crizotinib structure
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Common Name | 2-Keto Crizotinib | ||
|---|---|---|---|---|
| CAS Number | 1415558-82-5 | Molecular Weight | 464.320 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 679.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C21H20Cl2FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 365.0±31.5 °C | |
Use of 2-Keto Crizotinib2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib. |
| Name | 4-(4-{6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl}-1H-pyrazol-1-yl)-2-piperidinone |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib. |
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| Related Catalog | |
| In Vitro | 2-Keto Crizotinib (PF-06260182) is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 679.9±55.0 °C at 760 mmHg |
| Molecular Formula | C21H20Cl2FN5O2 |
| Molecular Weight | 464.320 |
| Flash Point | 365.0±31.5 °C |
| Exact Mass | 463.097809 |
| LogP | 3.09 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.688 |
| 4-(4-{6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl}-1H-pyrazol-1-yl)-2-piperidinone |
| 4-(4-{6-Amino-5-[(1R)-1-(2,6-dichlor-3-fluorphenyl)ethoxy]-3-pyridinyl}-1H-pyrazol-1-yl)-2-piperidinon |
| 2-Piperidinone, 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]- |
| 4-(4-{6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophényl)éthoxy]-3-pyridinyl}-1H-pyrazol-1-yl)-2-pipéridinone |