Amthamine dihydrobromide

Modify Date: 2024-01-03 12:52:58

Amthamine dihydrobromide Structure
Amthamine dihydrobromide structure
Common Name Amthamine dihydrobromide
CAS Number 142457-00-9 Molecular Weight 319.06
Density N/A Boiling Point N/A
Molecular Formula C6H13Br2N3S Melting Point N/A
MSDS USA Flash Point N/A

 Use of Amthamine dihydrobromide


Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

 Names

Name 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine,dihydrobromide
Synonym More Synonyms

 Amthamine dihydrobromide Biological Activity

Description Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].
Related Catalog
References

[1]. Trivendra Tripathi, et al. Hepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R-(-)-α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental Model. American Medical Journal. 2010, 1 (1): 1-7.

 Chemical & Physical Properties

Molecular Formula C6H13Br2N3S
Molecular Weight 319.06
Exact Mass 316.92000
PSA 93.90000
LogP 3.08150

 Safety Information

RIDADR NONH for all modes of transport

 Articles27

More Articles
Modulation of in vivo immunoglobulin production by endogenous histamine and H1R and H2R agonists and antagonists.

Pharmacol. Rep. 62(5) , 917-25, (2010)

The present study was designed to delineate the immunomodulatory role of histamine receptors (H1R and H2R) and their antibody generation in a rabbit model. Six groups containing 18 rabbits each receiv...

Analysis of the histamine H2-receptor in human monocytes.

Biochem. Pharmacol. 92(2) , 369-79, (2014)

Histamine receptors are G-protein-coupled receptors (GPCRs). Canonically, the histamine H2-receptor (H2R) couples to Gs-proteins and activates adenylyl cyclases (ACs) with subsequent adenosine-3',5'-c...

Disruption of histamine H2 receptor slows heart failure progression through reducing myocardial apoptosis and fibrosis.

Clin. Sci. 127(7) , 435-48, (2014)

Histamine H2 receptor (H2R) blockade has been reported to be beneficial for patients with chronic heart failure (CHF), but the mechanisms involved are not entirely clear. In the present study, we asse...

 Synonyms

cc-388
Amthamine dihydrobromide
Hispidulin
2-amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide
2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide
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