Amthamine dihydrobromide structure
|
Common Name | Amthamine dihydrobromide | ||
---|---|---|---|---|
CAS Number | 142457-00-9 | Molecular Weight | 319.06 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C6H13Br2N3S | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of Amthamine dihydrobromideAmthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1]. |
Name | 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine,dihydrobromide |
---|---|
Synonym | More Synonyms |
Description | Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1]. |
---|---|
Related Catalog | |
References |
Molecular Formula | C6H13Br2N3S |
---|---|
Molecular Weight | 319.06 |
Exact Mass | 316.92000 |
PSA | 93.90000 |
LogP | 3.08150 |
RIDADR | NONH for all modes of transport |
---|
~77% Amthamine dihyd... CAS#:142457-00-9 |
Literature: Eriks; Van der Goot; Sterk; Timmerman Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246 |
~% Amthamine dihyd... CAS#:142457-00-9 |
Literature: Eriks; Van der Goot; Sterk; Timmerman Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246 |
~% Amthamine dihyd... CAS#:142457-00-9 |
Literature: Eriks; Van der Goot; Sterk; Timmerman Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246 |
~% Amthamine dihyd... CAS#:142457-00-9 |
Literature: Eriks; Van der Goot; Sterk; Timmerman Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246 |
Precursor 3 | |
---|---|
DownStream 0 |
Modulation of in vivo immunoglobulin production by endogenous histamine and H1R and H2R agonists and antagonists.
Pharmacol. Rep. 62(5) , 917-25, (2010) The present study was designed to delineate the immunomodulatory role of histamine receptors (H1R and H2R) and their antibody generation in a rabbit model. Six groups containing 18 rabbits each receiv... |
|
Analysis of the histamine H2-receptor in human monocytes.
Biochem. Pharmacol. 92(2) , 369-79, (2014) Histamine receptors are G-protein-coupled receptors (GPCRs). Canonically, the histamine H2-receptor (H2R) couples to Gs-proteins and activates adenylyl cyclases (ACs) with subsequent adenosine-3',5'-c... |
|
Disruption of histamine H2 receptor slows heart failure progression through reducing myocardial apoptosis and fibrosis.
Clin. Sci. 127(7) , 435-48, (2014) Histamine H2 receptor (H2R) blockade has been reported to be beneficial for patients with chronic heart failure (CHF), but the mechanisms involved are not entirely clear. In the present study, we asse... |
cc-388 |
Amthamine dihydrobromide |
Hispidulin |
2-amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide |
2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide |