NBD-11021
Modify Date: 2024-04-06 08:23:00
NBD-11021 structure
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Common Name | NBD-11021 | ||
|---|---|---|---|---|
| CAS Number | 1427304-84-4 | Molecular Weight | 444.978 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H25ClN4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NBD-11021A small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction; inhibits the CD4-dependent virus in a dose-dependent manner with IC50 of 2.4 uM; also weakly shows HIV-1 RT inhibition with IC50 of 43.4 uM; exhibits pan-neutralization activity against a panel of 56 Env-pseudotyped HIV-1 representing diverse subtypes of clinical isolates (IC50 as low as 270 nM). HIV Preclinical |
| Name | NBD-11021 |
|---|
| Description | A small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction; inhibits the CD4-dependent virus in a dose-dependent manner with IC50 of 2.4 uM; also weakly shows HIV-1 RT inhibition with IC50 of 43.4 uM; exhibits pan-neutralization activity against a panel of 56 Env-pseudotyped HIV-1 representing diverse subtypes of clinical isolates (IC50 as low as 270 nM). HIV Preclinical |
|---|---|
| References | References 1. Curreli F, et al. J Med Chem. 2015 Sep 10;58(17):6909-6927. View Related Products by Target HIV HIV |
| Molecular Formula | C22H25ClN4O2S |
|---|---|
| Molecular Weight | 444.978 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NBD-11021
- Price: ￥Inquiry/25mg ￥Inquiry/100mg ￥Inquiry/500mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: NBD-11021
- Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: NBD-11021
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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