5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Modify Date: 2024-01-03 09:25:43

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite structure	Common Name	5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
	CAS Number	142808-44-4	Molecular Weight	869.89
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₅₀F₂N₅O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite

Description	5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₄₆H₅₀F₂N₅O₈P
Molecular Weight	869.89
Storage condition	2-8℃

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Use of 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Names

Biological Activity

Chemical & Physical Properties