OXF BD 02

Modify Date: 2024-01-20 14:36:31

OXF BD 02 Structure
OXF BD 02 structure
Common Name OXF BD 02
CAS Number 1429129-68-9 Molecular Weight 295.33
Density 1.2±0.1 g/cm3 Boiling Point 515.4±50.0 °C at 760 mmHg
Molecular Formula C18H17NO3 Melting Point N/A
MSDS N/A Flash Point 265.5±30.1 °C

 Use of OXF BD 02


OXF BD 02 is a selective inhibitor of BRD4(1) (the first bromodomain of BRD4) with IC50value of 382 nM[1].

 Names

Name 3-(3,5-Dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol
Synonym More Synonyms

 OXF BD 02 Biological Activity

Description OXF BD 02 is a selective inhibitor of BRD4(1) (the first bromodomain of BRD4) with IC50value of 382 nM[1].
Related Catalog
Target

BRD4(1):382 nM (IC50)

References

[1]. Hewings DS, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J Med Chem. 2013 Apr 25;56(8):3217-27.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 515.4±50.0 °C at 760 mmHg
Molecular Formula C18H17NO3
Molecular Weight 295.33
Flash Point 265.5±30.1 °C
Exact Mass 295.120850
LogP 2.54
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.616

 Synonyms

Benzenemethanol, 3-(3,5-dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-
3-(3,5-Dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol
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