1429129-68-9

1429129-68-9 structure

Name: OXF BD 02
Chemical Name: 3-(3,5-Dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol
CAS Number: 1429129-68-9
Molecular Formula: C₁₈H₁₇NO₃
Molecular Weight: 295.33
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2018-06-18 09:29:28
Modify Date: 2024-01-20 14:36:31
OXF BD 02 is a selective inhibitor of BRD4(1) (the first bromodomain of BRD4) with IC50value of 382 nM[1].

Name	3-(3,5-Dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol
Synonyms	Benzenemethanol, 3-(3,5-dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl- 3-(3,5-Dimethyl-1,2-oxazol-4-yl)-5-[hydroxy(phenyl)methyl]phenol

Description	OXF BD 02 is a selective inhibitor of BRD4(1) (the first bromodomain of BRD4) with IC50value of 382 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4(1):382 nM (IC50)
References	[1]. Hewings DS, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J Med Chem. 2013 Apr 25;56(8):3217-27.