Boc-O1Pen-OH * DCHA
Boc-O1Pen-OH * DCHA structure
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Common Name | Boc-O1Pen-OH * DCHA | ||
|---|---|---|---|---|
| CAS Number | 142929-49-5 | Molecular Weight | 219.235 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 391.2±22.0 °C at 760 mmHg | |
| Molecular Formula | C9H17NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 190.4±22.3 °C | |
Use of Boc-O1Pen-OH * DCHABoc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 391.2±22.0 °C at 760 mmHg |
| Molecular Formula | C9H17NO5 |
| Molecular Weight | 219.235 |
| Flash Point | 190.4±22.3 °C |
| Exact Mass | 219.110672 |
| PSA | 84.86000 |
| LogP | 0.55 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.462 |
| HS Code | 2924199090 |
|---|
|
~71%
Boc-O1Pen-OH * DCHA CAS#:142929-49-5 |
| Literature: MYREXIS, INC.; BAJJI, Ashok, C.; TANGALLAPALLY, Rajendra, P.; KIM, In, Chul; KIM, Se, Ho; PARKER, Daniel, P.; TROVATO, Richard; PAPAC, Damon, I.; YAGER, Kraig; BAICHWAL, Vijay, R. Patent: WO2012/148550 A1, 2012 ; Location in patent: Page/Page column 50; 51 ; |
|
~71%
Boc-O1Pen-OH * DCHA CAS#:142929-49-5 |
| Literature: Chandrakumar; Stapelfeld; Beardsley; Lopez; Drury; Anthony; Savage; Williamson; Reichman Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2928 - 2938 |
|
~75%
Boc-O1Pen-OH * DCHA CAS#:142929-49-5 |
| Literature: Adamczyk, Maciej; Fishpaugh, Jeffrey R.; Thiruvazhi, Mohan Organic Preparations and Procedures International, 2002 , vol. 34, # 3 p. 326 - 331 |
|
~%
Boc-O1Pen-OH * DCHA CAS#:142929-49-5 |
| Literature: Journal of Medicinal Chemistry, , vol. 35, # 16 p. 2928 - 2938 |
|
~%
Boc-O1Pen-OH * DCHA CAS#:142929-49-5 |
| Literature: Organic Preparations and Procedures International, , vol. 34, # 3 p. 326 - 331 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Acetic acid, 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- |
| {2-[(tert-Butoxycarbonyl)amino]ethoxy}acetic acid |
| [2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]acetic acid |
| AmbotzBAA5240 |