Boc-NH-PEG1-OH structure
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Common Name | Boc-NH-PEG1-OH | ||
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CAS Number | 26690-80-2 | Molecular Weight | 161.199 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 267.2±23.0 °C at 760 mmHg | |
Molecular Formula | C7H15NO3 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 115.4±22.6 °C | |
Symbol |
GHS05, GHS06 |
Signal Word | Danger |
Use of Boc-NH-PEG1-OHBoc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | tert-butyl n-(2-hydroxyethyl)carbamate |
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Synonym | More Synonyms |
Description | Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 267.2±23.0 °C at 760 mmHg |
Molecular Formula | C7H15NO3 |
Molecular Weight | 161.199 |
Flash Point | 115.4±22.6 °C |
Exact Mass | 161.105194 |
PSA | 58.56000 |
LogP | 0.49 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.450 |
Storage condition | 2-8°C |
Symbol |
GHS05, GHS06 |
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Signal Word | Danger |
Hazard Statements | H301-H315-H318-H335 |
Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | T:Toxic; |
Risk Phrases | R25;R37/38;R41 |
Safety Phrases | S26-S39-S45-S36/37/39 |
RIDADR | UN 2810 6.1/PG 3 |
WGK Germany | 3 |
Hazard Class | 6.1 |
HS Code | 2924199090 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Synthesis , 133, (1993)
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Synth. Commun. 21 , 359, (1991)
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tert-Butyl (2-hydroxyethyl)carbamate |
(2-hydroxyethyl)carbamic acid t-butyl ester |
Boc-NH-(CH2)2-1-naphthylamide |
boc-ethanolamine |
Boc-2-aminoethanol |
2-Boc-ethanolamine |
2-(tert-Butoxycarbonyl)ethanolamine |
2-(tert-ButoxycarbonylaMino)-1-ethanol |
(2-hydroxy-ethyl)-carbamic acid tert-butyl ester |
Carbamic acid, N-(2-hydroxyethyl)-, 1,1-dimethylethyl ester |
MFCD00056657 |
N-(t-butoxycarbonyl)-2-hydroxy-ethylamine |
N-(tert-Butoxycarbonyl)ethanolamine |
2-(Boc-amino)-1-ethanol |
N-(2-Hydroxyethyl)carbamic Acid tert-Butyl Ester |
boc-aminoethanol |
Boc-Gly-ol |
Boc-glycinol |
2-Methyl-2-propanyl (2-hydroxyethyl)carbamate |
N-Boc-ethanolamine |
tert-Butyl N-(2-Hydroxyethyl)carbamate |
2-(tert-butoxycarbonylamino)ethanol |
tert-butyl N-(2-hydroxyethyl)-carbamate |