391684-36-9

391684-36-9 structure
391684-36-9 structure
  • Name: Boc-NH-PEG6-CH2COOH
  • Chemical Name: 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid
  • CAS Number: 391684-36-9
  • Molecular Formula: C19H37NO10
  • Molecular Weight: 439.498
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-09 07:20:53
  • Modify Date: 2024-01-02 16:50:13
  • Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid
Synonyms 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid
3,8,11,14,17,20,23-Heptaoxa-5-azapentacosan-25-oic acid, 2,2-dimethyl-4-oxo-
Description Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 557.7±50.0 °C at 760 mmHg
Molecular Formula C19H37NO10
Molecular Weight 439.498
Flash Point 291.1±30.1 °C
Exact Mass 439.241760
LogP -1.24
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.467