1091627-77-8
1091627-77-8 structure
- Name: BocNH-PEG6-CH2CH2NH2
- Chemical Name: tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
- CAS Number: 1091627-77-8
- Molecular Formula: C19H40N2O8
- Molecular Weight: 424.53000
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-12-31 16:56:07
- Modify Date: 2024-02-03 17:21:07
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Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
|---|---|
| Synonyms |
t-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosylcarbamate
22-AMINO-5,8,11,14,17,20-HEXAOXA-2-AZADOCOSANOIC ACID 1,1-DIMETHYLETHYL ESTER Boc-NH-PEG6-CH2CH2NH2 |
| Description | Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C19H40N2O8 |
|---|---|
| Molecular Weight | 424.53000 |
| Exact Mass | 424.27800 |
| PSA | 123.22000 |
| LogP | 1.47410 |