BocNH-PEG6-CH2CH2NH2

Modify Date: 2024-02-03 17:21:07

BocNH-PEG6-CH2CH2NH2 Structure
BocNH-PEG6-CH2CH2NH2 structure
Common Name BocNH-PEG6-CH2CH2NH2
CAS Number 1091627-77-8 Molecular Weight 424.53000
Density N/A Boiling Point N/A
Molecular Formula C19H40N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BocNH-PEG6-CH2CH2NH2


Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 BocNH-PEG6-CH2CH2NH2 Biological Activity

Description Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H40N2O8
Molecular Weight 424.53000
Exact Mass 424.27800
PSA 123.22000
LogP 1.47410

 Synonyms

t-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosylcarbamate
22-AMINO-5,8,11,14,17,20-HEXAOXA-2-AZADOCOSANOIC ACID 1,1-DIMETHYLETHYL ESTER
Boc-NH-PEG6-CH2CH2NH2
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