![]() Me-PEG4-Me structure
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Common Name | Me-PEG4-Me | ||
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CAS Number | 143-24-8 | Molecular Weight | 222.279 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 275.3±0.0 °C at 760 mmHg | |
Molecular Formula | C10H22O5 | Melting Point | −30 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 140.6±0.0 °C | |
Symbol |
![]() GHS08 |
Signal Word | Danger |
Use of Me-PEG4-MeMe-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | tetraglyme |
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Synonym | More Synonyms |
Description | Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 275.3±0.0 °C at 760 mmHg |
Melting Point | −30 °C(lit.) |
Molecular Formula | C10H22O5 |
Molecular Weight | 222.279 |
Flash Point | 140.6±0.0 °C |
Exact Mass | 222.146729 |
PSA | 46.15000 |
LogP | -1.51 |
Vapour density | 7.7 (vs air) |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.421 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
![]() GHS08 |
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Signal Word | Danger |
Hazard Statements | H360Df |
Precautionary Statements | P201-P308 + P313 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi:Irritant; |
Risk Phrases | R19;R43 |
Safety Phrases | S36-S24 |
RIDADR | NONH for all modes of transport |
WGK Germany | 1 |
RTECS | SB0400000 |
HS Code | 2942000000 |
~% Me-PEG4-Me CAS#:143-24-8 |
Literature: Barnakov, Ch. N.; Volgin, A. A. Russian Journal of Applied Chemistry, 1993 , vol. 66, # 1.2 p. 152 - 155 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1993 , vol. 66, # 1 p. 182 - 185 |
~0%
Detail
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Literature: WO2005/87695 A1, ; Page/Page column 7-9 ; |
~% Me-PEG4-Me CAS#:143-24-8 |
Literature: Bulletin de la Societe Chimique de France, , p. 844,846 Journal de Chimie Physique et de Physico-Chimie Biologique, , vol. 54, p. 421,424 |
~% Me-PEG4-Me CAS#:143-24-8 |
Literature: WO2006/134081 A1, ; Page/Page column 6 ; |
~% Me-PEG4-Me CAS#:143-24-8 |
Literature: Industrial and Engineering Chemistry, , vol. 29, p. 548 Chem. Zentralbl., , vol. 109, # I p. 4534 US2111234 , ; |
HS Code | 2901100000 |
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Summary | 2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |
Radical Cationic Pathway for the Decay of Ionized Glyme Molecules in Liquid Solution.
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Development of bipolar all-solid-state lithium battery based on quasi-solid-state electrolyte containing tetraglyme-LiTFSA equimolar complex.
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Mechanism and Kinetics of Li2S Precipitation in Lithium-Sulfur Batteries.
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