9-(2-Deoxy-β-L-Ribofuranosyl)Adenine

Modify Date: 2024-01-13 18:56:13

9-(2-Deoxy-β-L-Ribofuranosyl)Adenine structure	Common Name	9-(2-Deoxy-β-L-Ribofuranosyl)Adenine
	CAS Number	14365-45-8	Molecular Weight	251.24200
	Density	1.91g/cm3	Boiling Point	627.2ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₃N₅O₃	Melting Point	186-187ºC
	MSDS	N/A	Flash Point	333.1ºC

Use of 9-(2-Deoxy-β-L-Ribofuranosyl)Adenine

2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV)[1].

Name	2'-Deoxy-L-adenosine
Synonym	More Synonyms

Description	2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
In Vitro	2'-Deoxy-L-adenosine shows anti-hepadnavirus activity, withour affecting the replication of 15 other RNA and DNA viruses, neither nor inhibiting human DNA polymerases (α, β, and γ) or compromise mitochondrial function[1].
In Vivo	2'-Deoxy-L-adenosine (p.o.; once daily) reduces viral load by as much as 108 genome equivalent/mL serum without drug-related toxicity in woodchuck efficacy model of chronic HBV infection[1].

Density	1.91g/cm3
Boiling Point	627.2ºC at 760 mmHg
Melting Point	186-187ºC
Molecular Formula	C₁₀H₁₃N₅O₃
Molecular Weight	251.24200
Flash Point	333.1ºC
Exact Mass	251.10200
PSA	119.31000
Vapour Pressure	1.36E-16mmHg at 25°C
Index of Refraction	1.863

HS Code	2934999090

Precursor 4
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