JAK2-IN-4

Modify Date: 2024-01-23 17:59:48

JAK2-IN-4 Structure
JAK2-IN-4 structure
Common Name JAK2-IN-4
CAS Number 1438284-00-4 Molecular Weight 469.56
Density N/A Boiling Point N/A
Molecular Formula C23H27N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JAK2-IN-4


JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].

 Names

Name JAK2-IN-4

 JAK2-IN-4 Biological Activity

Description JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].
Related Catalog
Target

IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].

References

[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83.

 Chemical & Physical Properties

Molecular Formula C23H27N5O4S
Molecular Weight 469.56