ML 315

Modify Date: 2024-04-06 21:52:57

ML 315 Structure
ML 315 structure
Common Name ML 315
CAS Number 1440251-53-5 Molecular Weight 374.22
Density 1.5±0.1 g/cm3 Boiling Point 558.0±50.0 °C at 760 mmHg
Molecular Formula C18H13Cl2N3O2 Melting Point N/A
MSDS N/A Flash Point 291.2±30.1 °C

 Use of ML 315


ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research[1].

 Names

Name ML 315 hydrochloride
Synonym More Synonyms

 ML 315 Biological Activity

Description ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research[1].
Related Catalog
References

[1]. Coombs TC, et al. Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3654-61.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 558.0±50.0 °C at 760 mmHg
Molecular Formula C18H13Cl2N3O2
Molecular Weight 374.22
Flash Point 291.2±30.1 °C
Exact Mass 373.038483
LogP 5.10
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.682

 Synonyms

MFCD30833328
5-(1,3-Benzodioxol-5-yl)-N-(3,5-dichlorobenzyl)-4-pyrimidinamine
4-Pyrimidinamine, 5-(1,3-benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-
ML315
5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride
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