Binodenoson
Modify Date: 2024-01-13 13:08:29
Binodenoson structure
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Common Name | Binodenoson | ||
|---|---|---|---|---|
| CAS Number | 144348-08-3 | Molecular Weight | 391.42 | |
| Density | 1.76g/cm3 | Boiling Point | 765.6ºC at 760mmHg | |
| Molecular Formula | C17H25N7O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 416.8ºC | |
Use of BinodenosonBinodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1]. |
| Name | 2-(cyclohexylmethylidenehydrazino)adenosine |
|---|---|
| Synonym | More Synonyms |
| Description | Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1]. |
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| Related Catalog | |
| In Vitro | Binodenoson (MRE-0470) (30-300 nM) decreases oxidative activity of tumor necrosis factor-α–primed FMLP-stimulated polymorphonuclear leukocytes in human whole blood and acts synergistically with Rolipram[1]. |
| In Vivo | Binodenoson (infused 0-0.9 μg/kg/h; adult Wistar rat; rat bacterial meningitis model), with or without rolipram (0-0.01 μg/kg/h), inhibits pleocytosis and reduces the lipopolysaccharide-induced increase in blood-brain barrier permeability (BBBP), indicative of decreased neutrophil-induced damage[1]. |
| References |
| Density | 1.76g/cm3 |
|---|---|
| Boiling Point | 765.6ºC at 760mmHg |
| Molecular Formula | C17H25N7O4 |
| Molecular Weight | 391.42 |
| Flash Point | 416.8ºC |
| Exact Mass | 391.19700 |
| PSA | 163.93000 |
| LogP | 0.65220 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.812 |
| sha 174 |
| wrc 0470 |
| mre 0470 |
| sha 211 |
| binodenoson |