Ald-CH2-PEG5-Boc

Modify Date: 2024-01-09 17:38:09

Ald-CH2-PEG5-Boc Structure
Ald-CH2-PEG5-Boc structure
Common Name Ald-CH2-PEG5-Boc
CAS Number 1446282-23-0 Molecular Weight 364.431
Density 1.1±0.1 g/cm3 Boiling Point 440.5±40.0 °C at 760 mmHg
Molecular Formula C17H32O8 Melting Point N/A
MSDS N/A Flash Point 189.0±27.4 °C

 Use of Ald-CH2-PEG5-Boc


Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Ald-PEG5-t-butyl ester
Synonym More Synonyms

 Ald-CH2-PEG5-Boc Biological Activity

Description Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 440.5±40.0 °C at 760 mmHg
Molecular Formula C17H32O8
Molecular Weight 364.431
Flash Point 189.0±27.4 °C
Exact Mass 364.209717
LogP -0.28
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.448

 Synonyms

ALD-CH2-PEG5-T-BUTYL ESTER
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