Tos-PEG6-CH2-Boc

Modify Date: 2024-01-10 10:41:53

Tos-PEG6-CH2-Boc Structure
Tos-PEG6-CH2-Boc structure
Common Name Tos-PEG6-CH2-Boc
CAS Number 1530777-90-2 Molecular Weight 550.659
Density 1.2±0.1 g/cm3 Boiling Point 611.2±55.0 °C at 760 mmHg
Molecular Formula C25H42O11S Melting Point N/A
MSDS N/A Flash Point 323.5±31.5 °C

 Use of Tos-PEG6-CH2-Boc


Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tos-PEG7-CH2CO2t-butyl ester
Synonym More Synonyms

 Tos-PEG6-CH2-Boc Biological Activity

Description Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 611.2±55.0 °C at 760 mmHg
Molecular Formula C25H42O11S
Molecular Weight 550.659
Flash Point 323.5±31.5 °C
Exact Mass 550.244812
LogP 1.14
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.490

 Safety Information

Hazard Codes Xi

 Synonyms

2-Methyl-2-propanyl 20-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15,18-hexaoxaicosan-1-oate
3,6,9,12,15,18-Hexaoxaeicosan-1-oic acid, 20-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
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