[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid

Modify Date: 2024-01-13 17:08:01

[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid Structure
[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid structure
Common Name [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid
CAS Number 1446282-24-1 Molecular Weight 358.35
Density N/A Boiling Point N/A
Molecular Formula C14H32O6P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid


[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid
Synonym More Synonyms

  Biological Activity

Description [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H32O6P2
Molecular Weight 358.35

 Synonyms

MFCD25424103