1446282-24-1

1446282-24-1 structure
1446282-24-1 structure
  • Name: [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid
  • Chemical Name: [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid
  • CAS Number: 1446282-24-1
  • Molecular Formula: C14H32O6P2
  • Molecular Weight: 358.35
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 01:23:27
  • Modify Date: 2024-01-13 17:08:01
  • [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid
Synonyms MFCD25424103
Description [10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H32O6P2
Molecular Weight 358.35