FPI-1465

Modify Date: 2024-01-02 13:40:36

FPI-1465 Structure
FPI-1465 structure
Common Name FPI-1465
CAS Number 1452458-70-6 Molecular Weight 350.35
Density N/A Boiling Point N/A
Molecular Formula C11H18N4O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FPI-1465


FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC50=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 µM, respectively[1].

 Names

Name FPI-1465

 FPI-1465 Biological Activity

Description FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC50=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 µM, respectively[1].
Related Catalog
References

[1]. Andrew M King, et al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.

 Chemical & Physical Properties

Molecular Formula C11H18N4O7S
Molecular Weight 350.35