LP-935509
Modify Date: 2024-01-02 23:23:02
LP-935509 structure
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Common Name | LP-935509 | ||
|---|---|---|---|---|
| CAS Number | 1454555-29-3 | Molecular Weight | 396.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LP-935509LP-935509 is a small-molecule adapter protein-2 associated kinase 1 (AAK1) selective and brain-penetrantinhibitor (IC50=3.3 nM), a ATP-competitive inhibitor with a Ki of 0.9 nM. LP-935509 is a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure[1]. |
| Name | LP-935509 |
|---|
| Description | LP-935509 is a small-molecule adapter protein-2 associated kinase 1 (AAK1) selective and brain-penetrantinhibitor (IC50=3.3 nM), a ATP-competitive inhibitor with a Ki of 0.9 nM. LP-935509 is a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure[1]. |
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| Related Catalog | |
| Target |
IC50: 3.3 nM (AAK1); 14 nM (BIKE); 320 nM (GAK)[1] |
| References |
| Molecular Formula | C20H24N6O3 |
|---|---|
| Molecular Weight | 396.44 |