2738877-85-3

2738877-85-3 structure

Name: Lp-PLA2-IN-5
Chemical Name: Lp-PLA2-IN-5
CAS Number: 2738877-85-3
Molecular Formula: C₂₃H₁₈F₅N₃O₄
Molecular Weight: 495.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
Create Date: 2022-04-17 09:36:00
Modify Date: 2024-01-10 15:13:00
Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32)[1].

Name	Lp-PLA2-IN-5

Description	Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
References	[1]. Zhenhua Gu, et al. Bridging cyclic pyrimidinones, methods of preparation thereof, compositions thereof and uses. Patent WO2021228159A1.

Molecular Formula	C₂₃H₁₈F₅N₃O₄
Molecular Weight	495.40